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Monday, September 30, 2019

Bullying in the Elementry School Essay

Every day we face situations that affect our diary to live. The children have a beautiful daily beginning, until they come to their school environment. There they found truly friends, but also children who damage them. The school harassment or â€Å"bullying† is a social problem that affects the majority of the children in our country and the world. The school harassment is the intimidation that a child creates, with power or force and aggression on one or more children to call the attention or simply to avoid to be one more. The â€Å"bullying† since better it is known refers to any act of physical or verbal aggression that it realizes one or more children against his homonyms. At the global level there is a phenomenon that affects the education of children and young people. This is manifested within the centers of education and has been for decades a serious problem that can bring repercussions to the students. Garcia (2011) indicates that the bullying cause serious damage to the mental and physical health in the people involved. It is inferred that the bullying is a problem, to the extent that we see as the students identify to this as an evil that harm permanently or part. Another reason is that it breaks with the expectations of society, which searches for a good school environment and therefore, it becomes an antisocial behavior reprehensible. To learn this behavior we must begin with the main participant, the aggressor. The aggressor is usually mostly feel need to dominate, are impulsive, show little empathy and are presented as people physically stronger. Olweus (1980) reaffirmed that it is natural to assume that they have developed a certain degree of hostility toward the environment, such feelings and impulses can make injure or harm to others causing them satisfaction. The aggressors may be people who work, study or provide services within the school and its grounds. We emphasize that the aggressor is not only the student but that involves other people. The spectator is an indirect aggressor, which according to Trautmann (2008), is the hearing of the aggressor and in which the aggressor is stimulated or inhibited by them. Any type of attacker can reach express violence with direct contact, psychological, emotional and the use of technology. These, the aggressor and the spectator or cooperator assault to another person, the victim, which suffers from all the aggressions. Galvez (2008), mentions that the victims usually are children that do not have the resources or skills to react, are little sociable, sensitive and fragile. Children who suffer from bullying are rejected by the other students and live in constant search of acceptance. These behaviors can have serious consequences for the physical and mental health of the victim permanently or part. From the right to education, physical, mental and the life, is that I am looking for studying this phenomenon as a social problem so that, identify their mode of operation, how to treat it and prevent it. Bullying The term bullying (Olweus, 1978) is now common in the literature on the topic of bullying among schoolchildren, to refer the situation of sustained violence, mental or physical, guided by an individual or by a group, directed at another individual in the group, who cannot defend themselves. The problem, being a new phenomenon, if it adopts new dimensions and it is worrying that our industrialized society that seems to have reached a certain level of welfare, employment of abuse and violence in school environments, paradoxically being detected ever so more alarmingly early age. The analysis of the problem offers some things to consider. It can be verbal, physical or psychosocial. Sometimes presents socially acceptable ways such as competitiveness academic, sports, social success, which in itself makes others feel inferior. It is necessarily repetitive behavior and causes pain at the time of the attack and sustained, to create an expectation on the victim of being white future attacks it is characterized by the dominance of the powerful over the weak in any context. The dynamic character bullying is â€Å"expansive† since its inception; a specific episode of abuse happens to be an assiduous dynamics of exclusion, violence and impaired socialization. It comes as a group phenomenon, from the moment that requires the support of the group and therefore, must be within the network of relationships that it is generated. Ramirez (2002) mentions that bullying is usually violent events among students and on occasion, there have been reports of violence by individuals outside the classroom to students. They identify certain behaviors as other forms of violence that affect the relationship between students and teachers, such as absenteeism, lack of participation and punctuality. It should be noted that in many of the cases, a student’s absences constant victim of harassment are to avoid being attacked, mocked at school and choose not to go to the classroom. Being one of the most common characteristics a victim of bullying. Areas affected by bullying Professor Dan Olweus was initiated investigations on the subject of bullying. At the beginning of 1970, Olweus began their investigations within schools in Norway, presenting a problem about assaults on persons; it is noteworthy that the institution had no interest on the subject. It was not until the 1980s that three young people between 10 and 14 years old committed suicide as a result of the activity of aggression upon them by their peers, thus arousing the attention of educational institutions on the problem. Education it is essential for the progress of a person and the country, also that it is a constitutional right. This phenomenon happens in all centers of education and in all its facets. Obviously affect the education of students to large scale and their mental, physical and emotional health. Because of this, it is vital that you consider this phenomenon as a problem and identify ways to treat it and prevent it. To achieve this, we must attack its root, which is located within the school facilities. It is important to study the bullying at the family level, since education starts at home, teaching behaviors to avoid that children create behavior hostile or conversely, too quiet. Also of utmost importance that the family is in constant orientation in order to keep your children from bullying and be able to identify when they are victims of this. Rodrigo (2004) says that family relations continue to be a relevant element in the analysis of behavior and lifestyle of the teenager. Aviles (2002) indicates that both the structural aspects of the educational institution and its dynamics are very important in explaining and, above all, prevent abuses among equals at the school. Polanin (2012) suggests that researchers and administrators of the school should consider the implementation of programs that focus on the supplementary behavior of transient bullying intervention and prevention programs. Cepeda, Pacheco, Garcia and Piraquive (2008), indicate that to learn if there is bullying, we must recognize that there is a relationship of power, power-submission, by one or more assailants on the victim and if the aggression has been consecutively. Attacks could be physical with some degree of aggression or psychological. Salmivalli (1999), comments that the aggressor is classified into two types, the predominantly dominant with antisocial tendency and the antisocial predominantly related to a low self-esteem. Recent research Del Prado (2011) notes that there has always been bullying and that many of the victims are marked for life. He mentions that according to statistics, 12 out of 100 students suffer bullying by peers. It indicates that victims choose to suffer isolation and a terrible fear of going back to school, clinging to silence as his only witness. Also infers that contrary to myth, the aggressor is not always bigger and stronger. This can be any child with low self-esteem need to get attention from their peers. He advises that we must ensure that the victim signals show how, insulation, etc. depressive symptoms. It concludes that a good interaction of the institution and parents is crucial in preventing this phenomenon, but that happened is the responsibility of the school. Traulsen (2011) this has been a drastic change of bullying. One of the new ways is cyber bullying, which is committed to social networks or technological means. Indicates that bullying can occur because of race, color, religion, sexual preference etc†¦ The victim did not reach the necessary maturity, fails to adequately address this situation. It is difficult for parents to detect that your child is being targeted because they tend to isolate themselves and hide the facts. For this family, school and government are essential to help combat this evil. The author infers that it is time to take drastic action against this phenomenon that is often taken for granted, so that in this way we ensure viable and proper education. Martinez (2005) investigated bullying and specific problems or patterns that occur in schools. The author conducted a review of the main conflicts of bullying, with the purpose of investigating and detecting possible solutions. We mentioned some factors that influence antisocial behavior as social inequality, the media, the motivation of the student and others. Refer some of antisocial behaviors that arise in the school as classroom disruption, indiscipline, vandalism, physical violence, psychological, social and in some cases, sexual assault. The conclusion is that using any direct remedy to remedy the phenomenon, beyond programs and techniques will be effective in resolving this conflict. Barcelo (2011) indicates that violence in the family learned and interactions with the environment influence bullying. He reports that for us to understand this phenomenon, teachers need to see this phenomenon as one of violence. Defines bullying as a type of violence where there are three participants who consist of the offender, victim and the spectators. The stalker uses different types of techniques from physical, verbal, psychological, social and racial harassment. As a result, the victim feels isolated and sometimes even can lead to dropout, suicide or retaliate against the aggressor to death. From here you have the need to intervene with this phenomenon and use punitive methods to the aggressor. And finally work with the victim, improving self-esteem and school environment. Teresa (2010) indicates that in the phenomenon of bullying are direct and indirect aggressors. Live is one who commits indirect aggression and has been the viewer. Mostly the harasser is narcissistic and needs of people who support or encourage them to commit their acts. Here is where the participation of the viewer aggressor, who plays a double role. On the one hand supports the harasser but the other is solidarity with the victim. This becomes a stalker and manipulator. Mention other accomplice’s classification called conscious or unconscious, the first known his actions and still participates. The second is usually a person close to the stalker who acts without realizing the facts. Study concludes that there are certain to classify accurately, what kinds of people are bullies. What if it could be located, is that bullies mostly come from the upper class. Methods to assess bullying Arzoz (2011) in his Thesis Analysis of the Situation and Proposed Intervention in an Education Center recommends an evaluation of intervention programs and techniques carried out in schools about bullying. He argues that it should take an individualized program in each school that meets the needs of them and take into account existing features. He points out that there is a shortage of technical or individualized treatments with students. Refers to the method of questionnaire on campuses is a good tool to detect bullying and work on time or remedy in cases where necessary. On the other hand emphasizes the validity of the method Pikas and teaching social skills as a factor in prevention. The author concludes that having prevention programs, we would reduce the phenomenon in question. Garcia (2011) states that as bullying phenomenon. This postulates that the lack of values, economics, drugs, among others, may be determining factors for violence in the perpetrator arises. Also emphasizes the serious damage this phenomenon generated on both sides: bully-victim, and that the best strategy is prevention. For this, we have developed a program that is based on parameter to the prevention and students involved in bullying. Within the prevention distinguishes three lines starring: education in emotions, feelings and values in cooperative group work and democratic management of coexistence. In the situation of students involved have proposed six programs which are: a) conflict resolution, b) peer support, c) quality circles d) development programs empathy, e) and f assertiveness programs ) the Pikas method. Emphasizes that despite the myths no spend this very worrying phenomenon that prevails in all schools at all levels.

Sunday, September 29, 2019

Hazards of Unsafe Driving Essay

Driving in and of itself is unsafe in its nature. The only thing keeping you connected to the ground is just four small patches of rubber. That is exactly why we should not take more risks while driving. Sure it may seem like you have layer of steel protecting you, but when you look at it, there is really not a lot between you and the ground when your going 50 miles an hour. The hazards of not following the rules of the road can be devastating. Not only can unsafe driving cause you to get a ticket and points against your license but it can also cause serious injury and sadly death in some cases. Must accidents are preventable by doing a few small things to insure your safety? I believe I read somewhere that some 95% of all accidents are driver error, which means nearly every single accident that occurs can be prevented by driving safely. One of the must common hazards of the roads is letting you get distracted by small things that you probably do nearly every time you sit behind the wheel of a car. In some cases, even more so with teenagers than any other group of people, other passengers in the car can distract you, you can get in a heated debate and begin to stop paying attention to the road and only to a passenger, fiddling with the radio is also another big one, I remember reading a story of a guy who reached in his backseat to change his tape and got in an accident and got killed because of it. Another big one is people see an accident and watch it instead of the road, sometimes almost causing them to become another accident. My mom once got in an accident by turning around for only just a second or so to see what my brother complaining about, the light was green when she looked back but quickly turned yellow, the car in front of her stopped and boomed, she hit it. It can only take a second or two of looking awa y to cause a dangerous situation that can be easily avoided. It can wait until the next red light or better yet when your off the road. Driving while tired is an enormous risk, I remember a few years back when a truck driver fell asleep at the wheel and caused an enormous crash on a freeway killing a few people, why you ask? Because he failed to take the  required 15 minute rest break that he was required by law to. Now you do not even have to worry about taking back movies late anymore, they have it to where you can just bring it in the next morning! There is really no reason to drive while tired, just have someone else drive, or if you are on a long road trip with no hotel in sight for a long time, just pull over to the road and take a little nap for 15-30 minutes to help you make it the rest of the way. Must people think turning up the music or opening a window helps them stay awake, but the fact is studies show that it does not matter a bit if you blast the music as loud as it will go or open a window on a freezing night. The best thing to do is to just not drive or have someone else drive for you who awake eno ugh to be able to drive responsible. A even bigger and probably the easiest risk to avoid while driving is wearing your seatbelt. Thousands of people die each year because they break the law and don’t do one of the easiest things possible, buckling up. Some people say they believe seatbelts can kill people. That is true seatbelts have killed and injured people. But they help way more than they hurt. Without them many people would be dead or seriously injured, they allow people who should have died in an accident to come out of it without a scratch. My grandfather died before I was even born, he died in a car accident and was thrown through his windshield, they say if he wore his seatbelt he would have lived. He died before I ever got to meet him. Why some people take that risk every day, I will never know, even my dad (on his side was the side of my family on which my grandfather died) hardly if ever buckles up, you would think of all people he would always buckle up because that’s how he lost his father. Some people think the air bag will save them but it’s simply not true if you want to make sure that you minimize your risks as much as possible you’ll buckle up. Road rage, is another very important unsafe driving hazard. Road rage has seemed too spurred to new levels in recent years as before it was very uncommon to hear of someone beating up another person for cutting them off. It is a fact of life when you drive you will be cut off, tailgated and whatnot. You just have to learn how to make sure that you can handle the situations to where you do not allow yourself to get angry enough to where you do something violent like that to harm another person or the property. Also a simple way to help make sure you’re not the victim of someone else road rage, if you know you did something wrong and cut someone off sometimes a simple wave of the hand in showing an apology is enough to cool someone off. Speeding, it seems like everyone does it right? Well the majority of people do, from what I can tell from people I’ve asked, driving with other people, and just looking out at the roads, it seems like everyone is in a hurry to get there, and get there now. Some people are not even in a hurry they just speed because there use to it, sure its normally only five over, but that still speeding, some people do it because they get a rush from going fast, others because they are in a hurry to get where they want to go, or there late. Some people do it just out of habit their use to going 30 in 25’s or 50 in 45’s because they normally won’t get pulled over for only going five over so they decide they’ll do it. While others do it but don’t mean to, sometimes when you drive for a long time you don’t release that your going 5-10 miles over. Speeding is probably the biggest hazard of driving that must people do, and it’s also one of the must dangerous people can do. Speeding can cause deadly accidents and can turn cars into something for the junkyard. Avoiding traffic signs or signals is another big one. My mom has been hit twice, one by someone who ran a red light and another by someone who ran a stop sign. In small neighborhoods where not too many cars come by, or late at night when it seems like you’re the only one on the road some people think there can’t possible be any other cars coming and decide to run it. Or they’ll see the yellow light from a distance and say to themself’s ‘I can make it’ when in fact they’ll actually be going through it because the time they get there it will be red. Must of the accidents I have seen in my life are at intersections where I can only assume it was because someone has run a red light. Many people don’t even slow down for yellows they speed up when they shouldn’t. Normally there’s that few seconds where the lights are changing and they can make it, but every now and than someone misjudges their timing and gets hit. Drinking and driving, easily avoidable by everyone, people like to drink, sometimes they don’t know when they should stop and become impaired. Some of them even try to get behind the wheel of a car. Sometimes a friend will take them home or let them stay at their house until they sober up but other times there not so luckily in keeping them off the road and the driver can’t even tell which side of the road there supposes to be on. I saw an accident on T.V. a few years back where a guy had been drinking during his entire day of fishing out at the lake and decided to go home. He swerved over into another guy’s lane at 70 miles an hour the other guy was forced off the road where he’s jeep flipped over. Luckily because the man was wearing a seatbelt he lived with no serious injury’s but his car was totaled. Sadly some people can’t even tell they’re drunk and think they’re fine. Sadly many people die a year because of this, I read so mewhere that in one summer more people die from drinking and driving accidents than the amount of people who died during the entire Vietnam war. Now that is a lot of death’s the can be prevented if people just don’t drive impaired. A lot of people drive the exact same when its raining or snowing. When in fact they should be giving themself’s a extra few seconds of room between them and the car in front of them and break sooner. When its raining and there’s even a little water on the ground when you go fast enough the car no longer even has contact with the ground but only the water, now that’s unsafe! A lot of people loose control of there cars and crash when there is icy or wet roads out. Its also very easily avoidable, giving yourself a few extra seconds going maybe 5-10 miles slower than one would normally go would almost eliminate any risk of driving in bad weather. Also if its raining to hard to where its making it nearly impossible to see through the windshield, pull over! Normally when it rains that hard it will only last for a few minutes or so. Pulling over for that time helps make sure that you don’t ram a person in front of you because you can’t see them. Driving to close behind someone, it takes you longer than you think to release something is wrong and than to move your foot to the break, in that crucial amount of time it could be to late, giving yourself distance from  the car in front of you is the easiest thing to do, just let off the gas and be at least 3 seconds in normal weather and a little longer in bad weather behind someone and you’ll be a lot safer. Not only is driving at a distance safer the driver in front will appreciate it greatly. We all know there’s nothing worse than thinking the guy behind us is about to ram the back of our car. Driving with faulty equipment, sometimes not the easiest thing to recognize but certainly a easy one to fix. You may not notice your light is burnt out or your single is not working right away as soon as it happens, but when you do you should have it repaired as soon as possible. Having your lights not working makes you incredibly less visible at night, nearly impossible to see at times depending on how dark outside it is. It helps a bunch to be able to tell where your going to other cars, not being able to single correctly with a turn single can make it really hard and frustrating the driver who didn’t know you were going to be moving into his or her lane. There’s really no reason to let a flat be a flat, now you can buy a can to fix small leaks and pay a quarter to have it filled up again. Maybe not the must dangerous hazard out there but certainly one to keep a eye on. Being prepared for situations is also a great idea to help minimize the risks of you getting into trouble out on the road, knowing where your hazard lights are in a panic can be invaluable. My mom in one of her accidents in a panic forgot where her hazard lights were, in the evening other cars could not tell she was stopped and not only was she hit once she was also hit again from behind because a car could not see her stopped in the middle of the road. Knowing not to panic in accidents insures your safety while driving and makes your odds for survival greater when in accidents. A large majority of people panic when involved in accidents and only cause greater damage to themself’s or others because they do not know how to properly respond to a situation. Knowing the driving laws where you live or are going! Its probably one of the must easiest things to miss, when I went to Arizona for the summer the speed limits in the city I was in was normally 35, I was not used to it, because  around here the speed limits on must main roads are 45! Watching for the signs can help you not become a hazard. Also when my dad came up here a few months ago for my sisters graduation he was unfamiliar with the ‘Michigan right’ as we like to call it, and had no idea he had to go right to go left. Sometimes it can be hard just to know the speed limits and other odds and ends in driving in your own area, becoming familiar with your own area is a good example to, must people miss the fact that Middlebelt is 40 and normally go much faster! Knowing your roads, the speed limits, and any other posted sign can be an enormous help in driving safely. Knowing where the cars around you are can also be a big help to, knowing where that motorcycle is so you don’t cut him off is invaluable, motorcyclists have virtually no protection from cars and if one gets hit that’s pretty much it for him or her that’s on it. Checking your blind spots, probably the #1 thing must people forgot to do is a huge thing, we all know there’s spaces you can not see if you just look straight ahead and only at your mirror . You do not want to just check your mirror and than smack right into someone because you were to lazy to glance in the direction you were going in. Its also a safe idea to not be right next to a car, they say if the car see’s a immediate danger to going to swerve into the closest lane, which normally in a two lane road would be where you are, they say to try and space yourself to where your not next to a car beside you, because if you don’t, and they see a danger odds are there coming for you and t he only other option you have is to go right into oncoming traffic. Not knowing what to do in certain situations is another huge one, a few months back when we had the power outage that took out many stop lights, must people did not know that a down traffic light is suppose to be treated as a four way stop unless a officer is there controlling the situation. Some people do not follow the directions of officers to go other directions and become a hazard to other responsible people who are following the directions giving to them by the officer. Others can get in the way of a fire truck or ambulance as there passing because they do not release there suppose to get over and out of the way so that they can pass quickly and not have to work there way through traffic. With every single example above there is several things in common, they can all be incredibly dangerous, sometimes even deadly, and they are all incredibly easy to avoid doing for the must part. Driving in and of itself is a very dangerous thing to do, Doing the things above only makes something that’s dangerous even more dangerous. Taking dangerous risks like those above can cost you more than just a few bucks from your wallet, a point or two against your drivers license, or a small insurance increase, it can cost you your life. Not only that but now a days its more important than ever to have a clean driving record. It helps show your responsible to employers and that you follow rules accordingly. If a job requires driving and you have a clean record compared to someone who has a few tickets, odds are there going to choose you instead. Health insurance, life insurance, some of there premiums are based off your driving record believe it or not! Driving safely won’t cost you anything but it can save you a ton of money. Not only that but the time you have to take off work to go to court, the fines you’ll pay, the insurance increase, its all just not worth it. Not only will you save your wallet, you might just save your life or someone with you, you do not want to be held responsible for the death of a friend who is in the car with you because you did not prevent it from happening when you could have, it would truly be a horrible thing to live with for the rest of someone’s life, knowing there responsible for the death of the friend or a family member. Driving safely is probably the easiest thing a person can do and driving safely far outweighs the benefits of driving carelessly.

Saturday, September 28, 2019

Epidemiology Essay Example | Topics and Well Written Essays - 1500 words

Epidemiology - Essay Example The most important objective is to make assessment about the injury incidence among Sri Lankan flight attendants and to depict the elements of onboard injuries (Agampodi, Dharmaratne and Agampodi, 2009, p. 1-2). The purpose of a good analytical technique is to be able to enumerate precisely each of the unidentified quantities that the laboratory will have to settle on (Maumy, Boulanger, Dewe, Gilbert and Govaerts, 2005). Assessing the occurrence of onboard injury requires the stipulation of the injuries of Sri Lankan flight attendants. One policy is to use measures, which take into consideration the quantitative nature of the onboard injury (Quantifying disease in populations, n.d.). The purpose of this assessment is to apply epidemiological concepts to critically review this given article. A vivid cross-sectional study was executed among Sri Lankan flight attendants. All flight attendants experiencing their annual physical condition and first aid preparation were encouraged to participate. Flight attendants who flew incessantly for a six-month phase prior to data compilation were incorporated in the study sample. Flight attendants experiencing preliminary training before their primary flight (novel recruits) and flight attendants who had not flown for 6 months (such as following childbirth) were kept out from the study (Agampodi, Dharmaratne and Agampodi, 2009, p. 2). The sample was not derived from a proper random sampling. It comprised of batches of flight attendants employed in the identical time period in dissimilar years. Diversities in training procedures could influence the result of the current study. Another restriction was recall bias. Accounting of injury is reliant on recollect, which count on individual traits, rigorousness of injuries and impact of the i njury on the individual (Agampodi, Dharmaratne and Agampodi, 2009, p. 4). Epidemiology is the study of how frequently ailments take place in

Friday, September 27, 2019

People with learning disabilities Case Study Example | Topics and Well Written Essays - 1500 words

People with learning disabilities - Case Study Example This has led to an increased number of people with learning disability (LD) and aging-related health problems such as dementia, which has resulted in changes in social and service delivery needs. Service needs for this population are further increased because of continued deinstitutionalization of people with LD, resulting in increased community presence of people with high physical and mental morbidities. Certain subgroups of people with LD have specific increased age-related risks, such as those with Down syndrome, who have genetically based increased risk for dementia (Janicki et al., 1999). Others , such as, those with Cerebral Palsy have been noted to have a high risk of physical aging related deterioration, particularly relating to mobility (Strauss et. al., 2004), sometimes starting in young adulthood. (Jahnsen, 2004) The existing demographic pattern of increased longevity in people with LD points to a continued future increase in the proportion of older adults with LD, but does not adequately address the more significant changes in the prevalence of associated physical, mental and behavioral problems, as well as functional deficits in these cohorts, which will have an impact on their need for support. Even in currently older adults with LD there is a dearth of broad, linked data that would be helpful to planners, but more problematically, these cohorts may not be good models for the future extrapolation. Current older adults have lived vastly different lives than cohorts who will be the older adults of tomorrow, and these differences will very likely have a profound effect on all aspects of intellectual, emotional, medical and functional outcomes in late life. Extrapolating care requirements for older adults with LD from older adults without LD is not appropriate, as those with LD have had more restricted life experiences, with reduced functional independence and coping skills, generally have no adult children to assist in late life functioning. (Jenkins, 2005) Services for Older People with Learning Disabilities in UK In recent years some remarkable changes have been noticed not only in the lifestyle of people with LD but also in the services provided to them. Rehabilitation of a number of such people back into the society has resulted into the closure of several LD institutions and hospitals, whereas in past it is evident through studies the such treatment periods used to be unknown and at times ended up with the death of patients. Such a policy change is actually a result of a publication "An Ordinary Life" (King's Fund 1980). This publication motivated the masses about the merits of spending life at home within the community in comparison with an isolated hospital or nursing home. This viewpoint of f normalization was later embraced by most of the supporting bodies function with older people with LD and normal community life was considered as more helpful for the rehabilitation of such a group (Wolfensberger 1972). Dagnan et al. (1998)

Thursday, September 26, 2019

Silla Buddhism and Hwarang by Richard Essay Example | Topics and Well Written Essays - 1000 words

Silla Buddhism and Hwarang by Richard - Essay Example Korea Kingdom recognized the instituted hwarang that embraced Sinitic Mahayana Buddhism as the state religion. There was massive changes in the kingdom in the 6th century where Sinitic-style kingship was embraced and formation of strong government (54). This has kicked out huge debate as to whether the Korean Kingdom was founded on   the Sinitic Mahayana Buddhism dynasty or otherwise: the debate and research are still on.Richard argued added that Hwarang was got from information stored in Kim Pusik’s. The Confucian approach indicated that there was close relationship among theBuddhist monks and hwarang in the Silla kingdom.   Buddhist monks comprised of Haedong kosung, chon and Samguk yusa who demonstrated a link between Buddhist beliefs and the hwarang practices. Hwarang is demostrated as sketchy, laconic and suggestive, it was considered to bear different differentiation. Scholars also found that it was likely that hwarang were modelled by King Chinhung. Buddhism religio n was significant to the hwarang (55). The author presents the fact that Hwarang offered wilderness training in miltary to the youths where they also leant their culture. We can therefore argue that the Hwarang   was a very important tool that propagated the cultural practices throughout gernerations. They were interested in information regarding where they came from and the meaning of hwarang. Hwarang was understood as flower of youths even though many scholars do not agree.Hwarang is believed to originate from Samguk Sagi (56).

Wednesday, September 25, 2019

Social Enterprises Assignment Example | Topics and Well Written Essays - 250 words

Social Enterprises - Assignment Example The report notes some of the most distinguishing features of a social enterprise that differentiate them from types of business, nonprofits and government agencies. First, they directly address special needs through their products and services by alleviating human sufferings from the disadvantaged society. As reports notes, it is different from the socially responsible business that strives for a positive change through indirect means such as funding education, building roads, using environmental -friendly raw materials and providing volunteers to aid the society. Furthermore, they are solid vehicles for job creation, economic growth and development in a community. Second, social enterprise use earned revenue strategies such as charitable contributions and public sector subsidies to pursue their aims and visions. The report further points out that social enterprises comprises of both non-profits who use business models to pursue their missions and for-profit who primary purpose is social in nature. The report however, refutes that social enterprise addresses the needs of the society directly, unlike social entrepreneurs. Some of the basic business models that social enterprise employ in their pursuit of their vision include retail, service and manufacturing that aid people alleviate and overcome employment barriers. They provide human and social services; fee-based consulting services; community development and financing

Tuesday, September 24, 2019

Physical and Psychological abuse on a child cause devasting and even Essay

Physical and Psychological abuse on a child cause devasting and even fatal consequences - Essay Example Abusers often raise abusers so it seldom stops in one generation. The goal would be to figure out what allows some abused children to grow up not being an abuser and use that to help others. Much more attention needs to be spent on child abuse. It needs the same attention as other public health issues, such as smoking and obesity. Only then can we find a cure for the problem that causes such pain for many. Children who have been abused may suffer long term effects. Those effects may be different for different children but the victimization creates symptoms ranging from self-doubt to self-loathing In some cases the effects of being a victim never go away while some with the correct support may turn this self-doubt or self-loathing into that of survival. Many studies have been done in an effort to predict what might be the effects for each child as they grow older This paper will discuss what child abuse actually is, how prevalent it is and what the long term effects are recent studies will be used to support information presented. Studies show that children who have been abused suffer long term affects, such as self doubt and self loathing as modes of survival. Child maltreatment or abuse is defined by the United Nations Convention on the Rights of the Child (UNCRC) as the abuse of power that might harm the childs health, survival, dignity, or development. This is the basis for their definition of violence against children which broadens the scope from just violence to include social and environmental harm (Widom, et. al., 2008). This definition involves most kinds of violence against children as most of them are power issues. Putting a child in a position of having no power strongly affects tat childs self esteem causing him to b less assertive against the perpetrator. Philip Hyden (1999) describes the symptoms of abuse that might be seen in the emergency room. There are many possible approaches to reporting child abuse but unfortunately

Monday, September 23, 2019

Virtue Ethics Personal Statement Example | Topics and Well Written Essays - 500 words

Virtue Ethics - Personal Statement Example This is because no man is truly virtuous and everyone has certain deficiencies to appropriate degrees when evaluated against good character. When the question turns towards practices in business, good character and virtuousness do not stand very well in today's world if survival and sustainability are he immediate goals of the business activity. This is because, in accordance with the given situation, one may have to resort to means that may not be harmful to anyone, but do not fall within the framework of righteousness. For example, if there is a severe competition in the market, then it is not desirable to give way to others thinking that everyone should have an equal share of the business. In fact, businesses would not exist for long if they went that way. According to me, the sole aim of any business would be to strive for the generation of good consequences not only for the business, but also for every other entity as far as possible. As such, I believe that this should be the sole guiding path for a business. If I were to adopt this path, then my intentions would be multi-faceted. The quest for good results would make me ensure that I provide for the needy to the maximum extent possible. Likewise, I also feel that the people and other entities I am involved or related to must also benefit as a result of my actions and the business' progress.

Sunday, September 22, 2019

Week 5 discusison and participation questions Essay

Week 5 discusison and participation questions - Essay Example The cycles differ in methodology, time requirements, documentation requisites, man hours needed, and complexity. The accounts payable account is very important because most acquisition and payment transactions go through that account. Due to the fact that the accounts payable account is usually material auditors often have to use extensive analytical procedures and tests of details of balances. Accounts payables can be defined as unpaid obligations for goods and services. The methodology to perform an audit of accounts payables is illustrated in the following steps: It is amazing how accurate and reliable independent audits of financial statements are. There are tens of thousands of audits performed yearly on public companies and auditors accurately determine when any material misstatement or fraudulent activity occurs. Two analytical procedures that can be used to compare data and information from the financial statements is vertical and horizontal analysis. The use of statistical models can help auditors determine the audit risk very accurately. Material misstatements can be identified accurately by the auditors when they have the full honest cooperation of the accounting and managerial staff. Your assessment of the importance of test controls is very accurate. If an auditor determines that the managerial staff established good internal controls the auditor has a better audit trail to follow. Substantive test are critical for auditors to determine whether a company is subject to audit risks. If a company has internal weaknesses within the accounting department substantive tests can detect these types of accounting anomalies. It is true that auditors often assumed that if the internal controls of the company are strong the risk of fraudulent behavior is lower. The ability of auditors to identify risks and ways to fix those risks to improve the efficiency of an operation is a value added proposition of auditing work. Substantive

Saturday, September 21, 2019

Security Risks for Computers at Home Essay Example for Free

Security Risks for Computers at Home Essay Individuals commonly associate computer security risks exclusively with thoughts regarding computers in businesses and corporations. However, even for an average user, computer security risks are indeed present especially if a connection to the internet is present (Wang, 2003). To some, having risks in relation to the use of personal computers at home may not pertain to anything of serious consideration. In reality though, if one considers the multitude of tasks usually done using the home computer, which often contain important personal data, then security threats for a home computer may be more serious than it is commonly thought of (United States Computer Emergency Readiness Team [USCERT], 2001). Therefore, it is important to assess the potential security threats and methods of attack that are related to home computer security. As mentioned, security threats for the home computer are a reality. In this sense, there are indeed numerous examples of potential security threats especially if one has a connection to the internet and constantly uses the different functions of the web. Some of the most common forms of security threats to home computers are in the form of Trojan horse programs and back door programs. Trojan horse programs are tools in which malicious files are allowed entry to the system upon the placement of the Trojan horse which usually takes the form of something that may not seem harmful based on the evaluation of a common user (USCERT, 2001). Given such functions and features, it is very much apparent as to why Trojan horse programs are called as such. As previously pointed out, back door programs are also examples of programs that pose a threat to home computers. Characteristically, back door programs, which are also referred to as remote administration programs, provide other individuals the means to control the home computer through a network connection (USCERT, 2001). Other home computer security risks come in vastly different forms. For one, an attack termed as denial of service, allow other individuals to incapacitate a home computer by placing extreme amounts of stress upon it in terms of data processing; in addition, it is commonly taken into consideration that individuals that aim to attack other home computers usually take advantage of home computers that they have already compromised (USCERT, 2001). As previously pointed out, home computer users are probably not as skilled in terms of providing protection for their computers and their networks as compared to those that use computers in large businesses and firms. In this sense, unprotected networking shares may be considered as potential entry points used for placing and triggering different security threats; also packet sniffing may be used to take advantage of how private information are sent through a common network (USCERT, 2001). In addition, mobile codes such as Java, Javascript, and even ActiveX as well as cross site scripting, may be used to compromise home computers and the users. Specifically, personal information may easily be attained through such codes and scripts if one is not careful (USCERT, 2001). Individuals that aim to cause harm towards home computer users take into account some of the most common tasks accomplished through the use of the internet. As mentioned, codes and scripts may be used to the detriment of a user during the course of web browsing. Email spoofing and email borne viruses are two of the most common concerns regarding email and its relation to home computer security. While email spoofing may be a form of trickery so that the user may assume that the sender of the information is rather trustworthy and will hence not be cautious in his or her reply, email borne viruses use trickery as well but also uses malicious codes in the form of cleverly disguised as attachments to various types of messages which is made worse by the fact that hidden file extensions may be taken advantage of to make a virus appear to be harmless (USCERT, 2001). In addition, chat clients are also considered to be of potential risk. The main reason for such as consideration is that chat clients are highly similar to email in terms of function (USCERT, 2001). Given a varied assortment of types of security threats to home computers, one may already develop a sense of understanding as to how attackers gain information from a computer system. One method or technique used by attackers is through disguising a security threat as something that seems harmless, as it is quite expectable that even the average user has a sense of what is harmful if it is blatantly evident (Wang, 2003). From the previous discussion, such an approach may be observed from the distribution of Trojan horses, malicious code and scripts on websites, and email and chat client viruses. Expectedly, if the disguised program or code is transferred into the home computer and it is run, then personal information may then be transferred to the attacker. Aside from such an indirect approach, attackers may also use direct approaches in taking personal and important information. As exemplified by packet sniffing and network and computer access through previous placement of a malicious program or through identification and manipulation of weaknesses in security, attackers may use immense technical knowledge to directly select and acquire the information that they need such as credit card numbers (Wang, 2003). In general, it is made evident from the points discussed that home computers are also at risk due to the presence of different potential security risks as well as various ways in which attackers may use such security risks. Home computers that are connected to the internet may be seen both as a source of convenience for users but may also be perceived as a possible tool in which important information utilized by the user may be threatened. There are ways in which the negative aspects of home computing and security risks may be minimized by developing a better understanding of such security threats and methods of attack. Therefore, even for home computer users, broadening the level of knowledge regarding such issues of concern is certainly not a waste of time.

Friday, September 20, 2019

Cerebral Autoregulation Mechanism | Report

Cerebral Autoregulation Mechanism | Report From: Biose Ifechukwude Joachim Introduction Cerebral autoregulation (CA) is the multifactorial vascular mechanism that maintains a constant cerebral blood supply in spite of fluctuations in the cerebral perfusion pressure (CPP) (Lassen, 1959; Tiecks et al., 1995). This mechanism thrives for CPP values within the range of 50-150 mmHg (Lassen, 1959; Paulson, Strandgaard and Edvinsson, 1990; Panerai, 1998) (Fig. 1). The vascular response involved in CA is rapid and so robust that hypertension (Eames et al., 2003; Serrador et al., 2005; Zhang et al., 2007) and aging (Eames et al., 2003; Fisher et al., 2008; Liu et al., 2013; Oudegeest-Sander et al., 2014) does not alter its physiological role. However, CA is compromised following pathologic conditions such as traumatic brain injury, intracerebral haemorrhage, stroke, hyper-perfusion syndrome, and subarachnoid haemorrhage (Diedler et al., 2009; Atkins et al., 2010; Budohoski et al., 2012; Saeed et al., 2013; Buczek et al., 2013). Fig. 1. Cerebral autoreglation in relation to vascular response. Within the upper and lower boundaries of the autoregulatory range (dotted lines), blood flow remains constant (blue line with beads). As Pressure falls below the lower limit, vascular smooth muscle relaxes to allow dilatation, while constriction of vessels (red circles) ensues to reduce blood flow as pressure approximates the upper limit. Adapted from Pires et al., 2013. Classification Based on factors affecting cerebral blood flow (CBF), CA can be classified into two categories, metabolic autoregulation (MA) and pressure autoregulation (PA). Mainly due to changes in brain tissue pH (Cotev and Severinghaus, 1969; Betz and Heuser, 1967; Raichle, Posner and Plum, 1970), MA is the principal regulatory mechanism of CBF according to metabolic demand. This implies that MA responds to local or global ischemia and hypoxia which increases pH by increasing CBF via vasodilatation (Ekstrom-Jodal et al., 1971; Raichle and Stone, 1971).While PA is the vascular response to maintain blood flow following changes in perfusion pressure, achieved by varying the degree of vasoconstriction or vasodilatation of the cerebral vasculature. Mechanism In adults and under normal conditions, provided CPP falls within the boundary of 50-150 mmHg, CBF is preserved at approximately 50 mL per 100 g of brain tissue per minute (McHenry et al., 1974; Strandgaard et al., 1976; Paulson, Strandgaard and Edvinsson, 1990). Outside this range of CPP, CA is impaired and CBF becomes directly dependent on mean arterial pressure (MacKenzie et al., 1976; Heistad and Kontos, 1979; Baumbach and Heistad, 1985; Paulson et al., 1990). More so, should CPP falls below the lower boundary of CA, blood flow reduces and ischemia sets in (Hossmann, 2006). The precise mechanism of CA is currently elusive; however, it is believed to be subject to the interaction of neurogenic, metabolic and myogenic factors (Czosnyka et al., 2009; Novak and Hajjar, 2010). Intrinsic innervation is touted to be directly involved in the mechanisms of CA (Goadsby and Edvinsson, 2002) and extrinsic pathway is implausible, since CA is unimpaired following sympathetic and parasympathetic denervation in experimental animals (Busija and Heistad, 1984). The perikarya within the subcortical region of the brain, precisely those from the nucleus basalis, locus ceruleus and raphe nucleus project to cortical microvessels for the control of local blood flow by release of neurotransmitters (ACH, norepinephrine and 5HT) (Hamel, 2006). These released neurotransmitter substances interact with the receptors on smooth muscle, endothelium, or astrocytes to cause constriction or dilation, thus regulating blood supply according to the metabolic demand (Iadecola, 2004; Hamel, 2006; Drake and Iadecola, 2007). Also, metabolic by-products released by the brain during CBF decrease are important for CA (Paulson, Strandgaar and Edvinsson, 1990). These substances, potassium, adenosine, and hydrogen ion triggers vasodilatation. Another important component of the CA mechanism is the myogenic response of the cerebrovascular smooth muscle in regulating vascular tone. Constriction of the cerebral vasculature due to smooth muscle contraction ensues during pressure fluctuations at the upper boundary of the autoregulatory range of CPP, thus blood flow is not excessive (Fig. 1). Conversely, fluctuations at the lower limit of CPP is followed by vasodilatation (Fig.1) (Kontos, 1978,Busija and Heistad, 1984; Mellander, 1989; Osol et al., 2002). Furthermore, the direct contact between astrocytes and the parenchymal arterioles of the brain have been shown to play a role in CA (Rennels and Nelson, 1975; Cohen, Molinatti and Hamel, 1997; Iadecola, 2004; Hamel, 2006; Drake and Iadecola, 2007; Zlokovic, 2008). Most microvessels at the subcortical level have astrocytic end-feet at the interface between them and neurons (Kulik et al., 2008), thus, under the direct influence of the vasoactive factors released by astrocytes (Murphy et al., 1994). Interestingly, the type of cerebral vasculature may also contribute to CA in an unexpected manner, with respect to their response to blood flow changes. While basilar artery dilates in response to increased blood flow, MCA constricts Koller and Toth, (2012). Under Anaesthesia Anaesthesia puts the brain in a state of reduced neuronal activity, as a result CBF decreases in light of neurovascular coupling (Attwell et al., 2010). Also, in their studies in rats, Jones et al., (2002) reported that anaesthesia reduces the CCP levels below the lower limit of CA. More importantly, anaesthetics have significant impact on CA as they affect the vasculature of the brain, directly or indirectly. Under the influence of volatile anaesthetics, calcium entry via voltage gated Ca2+ channels on vascular smooth muscle cells is reduced significantly, causing the vasculature to dilate (Bosnjak et al. 1992), thereby, directly overriding CA. Also, anaesthetics cause profound respiratory depression in spontaneously breathing animals, consequently PaCO2 increased. Given that the vasculature of the brain is highly sensitive to changes in CO2, an increase value of PaCO2 stimulates cerebral vasodilatation (Kuschinsky, 1997; Willie et al., 2014); correspondingly CBF increases (Figure 2). These effects of anaesthetics lead ultimately to the failure of CA in mammals. However, certain anaesthetics for example Ethomidate, preserves CA (Wang et al., 2010). This is mainly due to their ability to keep PaCO2 nearly constant within the nomal range without artificial ventilation (Lacombe et al. 2005; Joutel et al., 2010). Fig. 2. Cerebral blood flow with respect to arterial pressure of CO2. CBF increases as PaCO2 level increases beyond the level of 25 mmHg. However, at 80 mmHg blood vessels are maximally dilated and CBF remains constant with a further increase in PaCO2 values. Adapted from Adapted from Hill and Gwinnutt, no date. Stroke During arterial occlusion, as in the case of ischaemic stroke, local cerebral perfusion pressure falls below the normal CA range while MAP does not change. With persistent occlusion, autoregulation fails (Reinhard et al., 2008; Reinhard et al., 2012; Immink et al., 2005; Atkins et al., 2010) and regional CBF further decreases. For this reason, blood pressure changes, high or low, results in poor outcome (Castillo et al, 2004; Aslanyan et al., 2003; Sandset et al., 2012). However, this is not entirely due to the failed autoregulatory capacity of the vessels during ischemia, but perhaps their normal vasodilatory capacity has reached a maximal limit (Petersen et al., 2015). The impaired autoregulatory response following acute stroke has been observed both in the affected and contralateral hemispheres (Cupini et al., 2001; Dawson et al., 2000; Dawson, Panerai and Potter, 2003; Fieschi et al., 1988; Gelmers, 1982; Lisk et al., 1993; Hakim et al., 1989). References Aslanyan S, Fazekas F, Weir CJ, Horner S and Lees KR (2003). GAIN International Steering Committee and Investigators: Effect of blood pressure during the acute period of ischemic stroke on stroke outcome: a tertiary analysis of the GAIN International Trial. Stroke. 34: 2420–2425. Atkins ER, Brodie FG, Rafelt SE, Panerai RB and Robinson TG (2010). Dynamic cerebral autoregulation is compromised acutely following mild ischaemic stroke but not transient ischaemic attack. Cerebrovasc. Dis. 29: 228–235. Attwell D, Buchan AM, Charpak S et al. (2010). Glial and neuronal control of brain blood flow. Nature. 468: 232–43. Baumbach GL and Heistad DD (1989). Remodeling of cerebral arterioles in chronic hypertension. Hypertension. 13: 968–972. Betz E and Heuser D (1967). Cerebral cortical blood flow during changes of acid-base equilibrium the brain. J. Appl. Physiol. 23: 726-733. Bosnjak ZJ, Aggarwal A, Turner LA, Kampine JM and Kampine JP (1992). Differential effects of halothane, enflurane, and isofluurane on Ca2 + transients and papillary muscle tension in guinea pigs. Anesthesiology. 76: 123–131 Buczek J, Karlin ´ski M, Kobayashi A, BiaÅ‚ek P and CzÅ‚onkowska A (2013). Hyperperfusion syndrome after carotid endarterectomy and carotid stenting. Cerebrovasc. Dis. 35: 531–7. Budohoski KP, Czosnyka M, Smielewski P, Kasprowicz M, Helmy A, Bulters D et al. (2012). Impairment of cerebral autoregulation predicts delayed cerebral ischemia after subarachnoid hemorrhage: a prospective observational study. Stroke. 43: 3230–3237. Busija DW and Heistad DD (1984). Factors involved in the physiological regulation of the cerebral circulation. Rev. Physiol. Biochem. Parmacol. 101: 161–211. Castillo J, Leira R, Garcà ­a MM, Serena J, Blanco M and Dà ¡valos A (2004). Blood pressure decrease during the acute phase of ischemic stroke is associated with brain injury and poor stroke outcome. Stroke. 35: 520–526. Cohen Z, Molinatti G and Hamel E (1997). Astroglial and vascular interactions of noradrenaline terminals in the rat cerebral cortex. J. Cereb. Blood Flow Metab. 17: 894–904. Cotev S and Severinghaus JW (1969). Role of cerebrospinal fluid pH in management of respiratory problems. Anesth. Analg. 48: 42-47. Cupini LM, Diomedi M, Placidi F, Silvestrini M and Giacomini P (2001). Cerebrovascular reactivity and subcortical infarctions. Arch. Neurol. 58: 577–581. Czosnyka M, Brady K, Reinhard M, Smielewski P and Steiner LA (2009). Monitoring of cerebrovascular autoregulation: facts, myths, and missing links. Neurocritical Care. 10: 373–86. Dawson SL, Blake MJ, Panerai RB and Potter JF (2000). Dynamic but not static cerebral autoregulation is impaired in acute ischaemic stroke. Cerebrovasc. Dis.10:126–132. Dawson SL, Panerai RB and Potter JF (2003). Serial changes in static and dynamic cerebral autoregulation after acute ischaemic stroke. Cerebrovasc. Dis. 16:69–75. Diedler J, Sykora M, Rupp A et al. (2009). Impaired cerebral vasomotor activity in spontaneous intracerebral hemorrhage. Stroke. 40: 815–9. Drake CT and Iadecola C (2007). The role of neuronal signalling in controlling cerebral blood flow. Brain Lang. 102: 141–152. Ekstrom-Jodal B, Haggendal E, Linder LE and Nilsson NJ (1971). Cerebral blood flow autoregulation at high arterial pressures and different levels of carbon dioxide tension in dogs. Eur. Neurol. 6:6-10. Fieschi C, Argentino C, Toni D and Pozzilli C (1988). Calcium antagonists in ischemic stroke. J. Cardiovasc. Pharmacol. 12(6): 83–85. Fisher JP, Ogoh S, Young CN, Raven PB and Fadel PJ (2008). Regulation of middle cerebral artery blood velocity during dynamic exercise in humans: influence of aging. J. Appl. Physiol. 105: 266–273. Goadsby PJ and Edvinsson L (2002). Neurovascular control of the cerebral circulation, Lippincott Williams Wilkins, Philadelphia, Pa, USA. Gelmers HJ (1982). Effect of nimodipine (Bay e 9736) on postischaemic cerebrovascular reactivity, as revealed by measuring regional cerebral blood flow (rCBF). Acta Neurochir. (Wien). 63: 283–290. Hakim AM, Evans AC, Berger L, Kuwabara H, Worsley K, Marchal G, Biel C, Pokrupa R, Diksic M and Meyer E (1989). The effect of nimodipine on the evolution of human cerebral infarction studied by PET. J. Cereb. Blood Flow Metab. 9: 523–534. Hamel E (2006). Perivascular nerves and the regulation of cerebrovascular tone. J. Appl. Physiol. 100: 1059–1064. Heistad DD and Kontos HA (1979). In: Handbook of Physiology: The Cardiovascular System III, Berne RM, Sperelakis N (Eds.). Bethesda, MD: American Physiological Society.  137–182. Hossmann KA (2006). Pathophysiology and therapy of experimental stroke. Cell Mol. Neurobiol. 26: 1057-1083. Iadecola C (2004). Neurovascular regulation in the normal brain and in Alzheimer’s disease. Nature Reviews Neuroscience. 5(5): 347–360. Immink RV, van Montfrans GA, Stam J, Karemaker JM, Diamant M and van Lieshout JJ (2005). Dynamic cerebral autoregulation in acute lacunar and middle cerebral artery territory ischemic stroke. Stroke. 36: 2595–2600. Jones SC, Radinsky CR, Furlan AJ et al. (2002). Variability in the magnitude of the cerebral blood flow response and the shape of the cerebral blood flow pressure autoregulation curve during hypotension in normal rats [corrected]. Anesthesiology. 97: 488–96. Joutel A, Monet-Lepretre M, Gosele C, Baron-Menguy C, Hammes A, Schmidt S, Lemaire-Carrette B, Domenga V, Schedl A, Lacombe P and Hubner N (2010). Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease. J. Clin. Invest. 120: 433–445. Koller A and Toth P (2012). Contribution of flow-dependent vasomotor mechanisms to the autoregulation of cerebral blood flow. J. Vasc. Res. 49: 375–389. Kontos HA, Wei EP, Navari RM, Levasseur JE, Rosenblum WI and Patterson JL, Jr (1978). Responses of cerebral arteries and arterioles to acute hypotension and hypertension. Am. J. Physiol. 234: H371–H383. Kulik T, Kusano Y, Aronhime S, Sandler AL and Winn HR (2008). Regulation of cerebral vasculature in normal and ischemic brain. Neuropharmacology. 55: 281–288. Kuschinsky W (1997). Neuronal-vascular coupling. A unifying hypothesis. Adv. Exp. Med. Biol. 413: 167–176. Lacombe P, Oligo C, Domenga V, Tournier-Lasserve E and Joutel A (2005). Impaired cerebral vasoreactivity in a transgenic mouse model of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy arteriopathy. Stroke. 36: 1053–1058. Lassen NA (1959).Cerebral blood flow and oxygen consumption in man. Physiol. Rev. 39: 183–238. Lassen NA (1974). Control of cerebral circulation in health and disease. Circ. Res. 34: 749–760. Lisk DR, Grotta JC, Lamki LM, Tran HD, Taylor JW, Molony DA and Barron BJ (1993). Should hypertension be treated after acute stroke? A randomized controlled trial using single photon emission computed tomography. Arch. Neurol. 50:855–862. Liu J, Zhu YS, Hill C, Armstrong K, Tarumi T, Hodics T, Hynan LS and Zhang R (2013). Cerebral autoregulation of blood velocity and volumetric flow during steady-state changes in arterial pressure. Hypertension 62: 973– 979. MacKenzie ET, Strandgaard S and Graham DI et al. (1976). Effects of acutely induced hypertension in cats on pial arteriolar caliber, local cerebral blood flow, and the blood-brain barrier. Circ. Res. 39:33-41. McHenry LC, Jr., West JW, Cooper ES, Goldberg HI and Jaffe ME (1974).Cerebral autoregulation in man. Stroke. 5: 695-706. Mellander S (1989). Functional aspects of myogenic vascular control. J. Hypertens. 7(4): S21–S30. Murphy S, Rich G, Orgren KI, Moore SA and Faraci FM (1994). Astrocyte-derived lipoxygenase product evokes endothelium-dependent relaxation of the basilar artery. J. Neurosci. Res. 38: 314–318. Novak V and Hajjar I (2010). The relationship between blood pressure and cognitive function. Nature Reviews Cardiology. 7: 686–98. Osol G, Brekke JF, McElroy-Yaggy K and Gokina NI (2002). Myogenic tone, reactivity, and forced dilatation: a three-phase model of in vitro arterial myogenic behavior. Am. J. Physiol. Heart Circ. Physiol. 283: H2260– H2267. Oudegeest-Sander MH, van Beek AH, Abbink K, Olde Rikkert MG, Hopman MT and Claassen JA (2014). Assessment of dynamic cerebral autoregulation and cerebrovascular CO2 reactivity in ageing by measurements of cerebral blood flow and cortical oxygenation. Exp Physiol. 99: 586–598. Panerai RB (1998). Assessment of cerebral pressure autoregulation in humans—a review of measurement methods. Physiol. Meas. 19: 305–338. Paulson OB, Strandgaard S and Edvinsson L (1990). Cerebral autoregulation. Cerebrovasc. Brain Metab. Rev. 2: 161-192. Petersen NH, Ortega-Gutierrez S, Reccius A, Masurkar A, Huang A and Marshall RS (2015). Dynamic Cerebral Autoregulation Is Transiently Impaired for One Week after Large-Vessel Acute Ischemic Stroke. Cerebrovasc. Dis. 39: 144–150. Pires PW, Dams Ramos CM, Matin N and Dorrance AM (2013). The effects of hypertension on the cerebral circulation. Am. J. Physiol. Heart. Circ. Physiol. 304: 1598–1614, Raichle ME and Stone HL (1971). Cerebral blood flow autoregulation and graded hypercapnia. Eur. Neurol. 6: 1-5. Reinhard M, Wihler C, Roth M, Harloff A, Niesen WD, Timmer J et al. (2008). Cerebral autoregulation dynamics in acute ischemic stroke after rtPA thrombolysis. Cerebrovasc. Dis. 26: 147–155. Reinhard M, Rutsch S, Lambeck J, Wihler C, Czosnyka M, Weiller C et al. (2012). Dynamic cerebral autoregulation associates with infarct size and outcome after ischemic stroke. Acta  Neurol. Scand.125: 156–162.   Rennels M and Nelson E (1975). Capillary innervation in the mammalian central nervous system: an electron microscope demonstration (1). Am. J. Anat. 144: 233–241. Saeed NP, Panerai RB and Robinson TG (2013). The carotid artery as an alternative site to the middle cerebral artery for reproducible estimates of autoregulation index. Ultrasound Med. Biol. 39: 735–741. Sandset EC, Murray GD, Bath PM, Kjeldsen SE and Berge E (2012). Scandinavian Candesartan Acute Stroke Trial (SCAST) Study Group: Relation between change in blood pressure in acute stroke and risk of early adverse events and poor outcome. Stroke. 43: 2108–2114. Serrador JM, Sorond FA, Vyas M, Gagnon M, Iloputaife ID and Lipsitz LA (2005). Cerebral pressure-flow relations in hypertensive elderly humans: transfer gain in different frequency domains. J. Appl. Physiol. 98: 151–159. Strandgaard S (1976). Autoregulation of cerebral blood flow in hypertensive patients. The modifying influence of prolonged antihypertensive treatment on the tolerance to acute, drug-induced hypotension. Circulation. 53: 720-727 Tiecks FP, Lam AM, Aaslid R and Newell DW (1995). Comparison of static and dynamic  Cerebral autoregulation measurements. Stroke. 26: 1014–1019. Wang Z, Schuler B, Vogel O, Arras M and Vogel J (2010). What is the optimal anesthetic protocol for measurements of cerebral autoregulation in spontaneously breathing mice? Exp. Brain Res. 207: 249–258. Willie CK, Tzeng YC, Fisher JA and Ainslie PN (2014). Integrative regulation of human brain blood flow. J. Physiol. 592: 841–859. Zhang R, Witkowski S, Fu Q, Claassen JA and Levine BD (2007). Cerebral hemodynamics after short- and long-term reduction in blood pressure in mild and moderate hypertension. Hypertension. 49: 1149–1155. Zlokovic BV (2008). The blood-brain barrier in health and chronic neurodegenerative disorders. Neuron. 57: 178–201.